Columbia Public Health
Scientists Discover Robust Evidence That Chronic Fatigue Syndrome (ME/CFS) Is a Biological Illness
Scientists at the Center for Infection and Immunity at Columbia’s Mailman School of Public Health have identified changes in the immune system of people with chronic fatigue syndrome, known medically as myalgic encephalomyelitis. These findings are provide the most definitive evidence to date that the condition is biologically based, not psychological.
The large, multicenter study, published on February 27 in the journal Science Advances, presents evidence of increased amounts of certain immune molecules called cytokines in patients who had the disease three years or less that were not present in those with the disease for longer periods or in those without the disease.
In a video interview, lead researcher Mady Hornig, MD, associate professor of epidemiology, explains that the findings could help improve diagnosis and identify treatment options for the disabling disorder, which has symptoms that range from extreme fatigue and difficulty concentrating to headaches and muscle pain.
Tangible substantiation of disease and the possibility of a blood test is a game-changer for people with the disease, says Hornig, who is also director of translational research at the Center for Infection and Immunity. “This can bring individuals who have been denied a diagnosis, and denied recognition of their illness… to an early diagnosis that may in addition tell us something about what is causing their illness and how potentially to treat it.”
Chronic fatigue syndrome, also known as myalgic encephalomyelitis is disease, a biological disease, that has symptoms that range from extreme fatigue and headaches to problems concentrating as well as muscle pain– very broad range of symptoms, And up to two-and-a-half million Americans are thought to have it. What we've found is that there are changes in the blood that we can use to identify individuals in the early phases of the disease, and by early we mean three years or less after the onset of symptoms and we believe that these types of blood tests may be able to help clinicians make a diagnosis more rapidly. Up to 70 percent of people have a delay in their diagnosis for at least a year and sometimes more than 10 years. It's really important to get the diagnosis as early as possible so that we can at least begin to be thinking about treatment strategies. We found evidence that strongly supports for the first time I think in a very large cohort of subjects that we are seeing a disorder that is not psychological but is biological. Patients are often left wondering why they're just not getting better maybe they're not trying hard enough and pulling up on the old bootstraps it is something that is not a matter of a will to get better, it's a matter of a physical condition that is preventing people from getting better. The disease has distinct stages and probably there are distinct treatments that are appropriate for those different stages. We can measure this in the blood with a blood test this can bring individuals who have been denied a diagnosis and denied recognition of their illness it can bring them to an early diagnosis that may in addition tell us something about what's causing their illness and how potentially to treat it.
#Scientists #Discover #Robust #Evidence #Chronic #Fatigue #Syndrome #MECFS #Biological #Illness
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I think maybe this is the impact of the digital age on youth, being glued to the screen 24/7 and growing up like that
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COMPLETE USELESS NOTHING BURGER.
DOCTORS KNOW NOTHING ABOUT THIS. Loathsome idiots. IDIOTS. THERE IS NO DIAGNOSIS OR TREATMENT. NO ONE TREATS THIS. IDIOTS. MORONS. HOPELESS
10 years later and where are we? Nowhere!
I'll be seeing my doctor about this condition next month
I cured my M.E/C.F.S with a heavy metal and candida detox. High quality Chlorophyll etc for the heavy metals. Research candida diet. May you heal. May the Gods bless you 💛
Mine wasa due to past exposure to work place toxins, but I was fortunate to find an enviromental Dr in the UK, back in 2001. Up until then many of the Drs just fobbed me off, except for one who put my health problems down to P.V.F.S. For which I guess that her hands were tied, as she couldn't say that it might be works related……. I think since the C19 Virus more Drs seem to atleast try to understand that a pretty large number of people can & do have a myriad of health problems
The constant bombardment of poisons, 'EVERYWHERE', throughout our world. Then the extreme deterioration of the family unit. The constant danger of violence at any moment, anywhere, at any time. Fight or Flight. The ever increasing movement of society to be Sociopathic, Narcissistic, all about me. Seeing fault in everything, everyone else says and does because you are self centered. Lying. Addcted to chaos. Only briefly thinking you are happy if you make someone else more miserable than yourself. Having no control over your feelings like a small child. No self accountability. Character Assasination. No trust of others because of these things. Thinking these behaviors are somehow acceptable because those you hang around are just like that. You become who you surround yourself with. And add that it is harder for most to merely survive with the dwindling resources available in their immediate lives. Illicit Drugs everywhere. Alcohol. Gee, I wonder what that does to the Chemical, Hormonal and Biological prisons of our bodies over time ? Yes, it would cause Biological changes. But everything else has to be accounted for. And addressed. But who's gonna actually do that ? Stop the chemicals flowing from every direction ? Embedded in Every Single Substance We Encounter. Poisoned by greed for decade after decade after decade. With only ever increasing abundance to infinity and beyond.
Then … Imagine if you will … that as people age their skin in their face is increasingly sagging. Forehead skin sags downward toward the eyes. Eyebrows press on eyelids that give the signal to the brain that we are tied. If this might be you, then lightly pinch that growing fold of skin from at your eye socket up over your eyebrow and lift it off of you eyelids. You will probably notice that some of that tiredness is alleviated if you hold that excess skin up for 10 to 15 seconds and reevaluate the drowsiness around your eyes.
IT'S HORMONAL. NOT INFECTIOUS. THE HPA AXIS.
My last dr fully understood that I had a nasty virus and just didn’t get better this was 1999 onwards I was bedbound for 17 – 18 years I still have extreme fatigue my day starts at around 10am and I’m utterly wiped out in pain by 4pm at the latest but I was pleased I had a small life but a life again. Recently started passing out again and as before cannot regulate my body temp either drenched and baking or so cold I’m in bed with 2 sweat shirts on bed socks etc. my GP retired and I thought ME was accepted now, the gp I saw said all cases of ME/CFS are caused by childhood trauma my childhood wasn’t ideal but love my mum and always felt loved. The dr won’t accept this saying book an hour slot and we get to the bottom of this and get you well! I nodded I felt awful anyway when I came out my husband said WHAT? I said I know but I always say I doubt you beleive in me/cfs – it’s my way of not feeling as awkward about saying it. I saw a specialist in ME/CFS who said it was definitely the virus I had and my body couldn’t cope. I checked what the NHS website said no sign of childhood trauma at all.
I feel like I am back to where I started all those years ago I can’t believe this young dr said this!! She’s running tests to rule out a medical reason but is sure there won’t be any. What would you guys do? If I’m with my husband he shuts anything like down right away. I feel lost and confused I have brain fog too and sleep too much or not enough I fallen asleep with food in my mouth but was so much better I had covid and a small stroke and was in hospital for both this year. Oh the dr also said childhood trauma can cause cancer autoimmune illness and heart issues. She said show me an ill person and will find childhood trauma anyone else surprised to say the least? She said there’s a dr on you tube that explains this very well but I really do not think this is reason I have this x
Never said what blood work!!!
What kind of blood tests? Does anybody knows where in EU it is possible to do them?
I was diagnosed with m.e after a very rare severe gland infection left me in constant pain and tired all the time as well as constant brain fog headache dizzyness I love in UK
HPA AXIS.YOUR TESTS SHOW YOUR RESPONSE IS "ADEQUATE." IT IS NOT! "WITHIN NORMAL LIMITS" IS NOT TRUE FOR YOU. IT IS NOT "ADEQUATE." FOR YOU. I KNOW.THEY DESTROYED MY LIFE, TOO.
I read a study that Methlyphenidat substantially reduces the symptomps of many people that suffer chronic fatigue. That study is from 2006 and was published in the american journal of medicine. Easy to find on google. Got 72 others studies citing this one. I only ended up looking it up when I began my adhd therapy which started this year as I got only now my diagnosis. I was very surprised how effective it was in pushing my own fatigue back. I thought maybe this is just a short boost and be quickly over. But now I am taking this for 6 months straight. And it is still working the same. And every time I am off for a few days I get a painful reminder that my fatigue has not gone away. It sucks to be dependent constantly on a drug to function. But after more than 20 years of fatigue I am grateful to god that I found something that has a direct noticable impact. My family witnessed a night and day difference with me because of it.
Modafinil for 3 days and I have some energy…I could cry!
Blood tests? Like many – our labs are great.
I hope this helps someone. I’ve suffered from CFS for as far as I can remember & it’s gotten worse over the years. I’ve recently discovered the root cause was genetic Classical EDS. That means the collagen in all my body is not normal thus the constant pain esp with age since collagen degrades with age. The best thing has been for me is taking Vitamin C & doing Keto with zero sugar (use substitutes like Splenda). This makes a huge difference for me & it makes sense since carbs break down collagen. It’s a struggle doing keto since carbs are in most foods. I try to always keep English Cucumbers on hand to avoid eating any carb which bring on the pain. If you’ve tried everything & nothing is working give this a try & please do not take narcotics or addictive drugs like Wellbutrin or Amphetamine, they will cause a whole new issue by themself. Free Palestine! 🇵🇸
What are the blood tests?
"What great advice! I love the ANTI-FATIGUE PACK from Planet Ayurveda —definitely keeps me going when I need it most."
It says it in the description but like most doctors they buried the lead… The BLOOD TEST is a: CYTOKINES PANEL. Hope that helps someone out there. ❤
I have finally been given a diagnosis after 39 years of symptoms which began 42 years ago with Fibromyalgia. After getting the first diagnosis of Fibromyalgia in 1982, which caused bouts of various symptoms but didn't stop me from being a wife and mother and supply teacher. But in 1985, I returned to university in Brandon, MB to finish my 4 year B.Ed degree so that I could return to full time teaching. I did graduate, in a wheelchair, I did teach, from a wheelchair, for 3.5 months until I couldn't sit up anymore. I eventually lost my marriage as well as my career and even some friends over the years just dropped me. But a chance reading that my younger brother found and sent on to me described what I most likely had. I showed the research to my doctor and she agreed that this was what I have. FINALLY!! I hate that I was forced to see a psychiatrist, told by the neurologist that first of all, I had MS, then told by another one that it was all in my head and many doctors later, I finally too gave up seeking answers, Even my family said I needed to try harder, get behind the wheel of my car and drive a little more each day until I got up to being able to drive the 8 hours back to see my parents. I still have to use hand controls to drive more than about 3 blocks. I still can't volunteer for organizations because the disease is so variable that I can't commit to a set schedule and organizations don't want someone who can't commit. I had to move to a new town almost 8 years ago and I still haven't met many new friends because I lead such an isolated life. My church is the same with lack of friendships. This disease made one of my doctors say, 'But Sharon, you have so much wrong with you! It is no wonder I made a mistake!' Gaslighting! My sympathies to all people who suffer with this horrible illness. All I can say to you is take it one day at a time or as my dad said to me 35 years ago, if that doesn't work, take it one hour at a time, or one second at a time. Just keep on living the best way you can. God bless you all!
31 years here. My GP banged his desk and shouted, “why won’t you accept, you are mentally ill”. In 1995. Not back since .
There is more garbage info out here on CFS than most other subject.
21 years with CFS. Getting tested for lyme next week. 20 years to find a good doctor. I will fire a doctor quicker than anyone else in the service industry.
What’s the blood test?
It is a fake disorder that only affects women from the first world. Weird that CFS isn’t too present in countries where women can’t afford to stay home from work
Thank you, a great accurate short video that summarize my problem, so I send this video to anyone asks me what is my issues!!!
Suffered for 24 years, completely bedbound, it’s like a living death
Sunny Trace
What is the blood test?
What is the blood test?
So what's the test? 🤷🏼♀️
What on Earth treatment strategies could western medicine have? She is a fantasist.
I don't agree with the speculation that this is purely a biological condition. But this does not make it less real.
What are the names of the blood tests?
There are a lot of hypochondriacs who now have CFS
And it’s hard to distinguish who’s genuine and who’s fake
Long haul Etiological diseases too, like what covid has proven.
They are not looking in the right areas of the body.
ME/CFS/FMS/POTS = Adrenal gland illness. It's our adrenal glands that aren't able to work right because of a physiological stress. Not emotional.
It's our blood sugar imbalance that is kicking the crap out of our adrenal glands.
High carbs, not enough protein, skipping meals, and more are like a karate kick to your adrenal glands.
Balance your blood sugar 24/7. Omit blatant sugar, add healthy protein and fat with eat meal. No caffeine, nothing but water to drink.
Those are the basics. Do that for a week, see how much more better you feel.
For those with Leaky Gut, bc LG is usually present with adrenal gland iisues, chopping raw garlic and putting in food will do wonders for your micro biome. Probiotics are a waste of money.
I did this for 4 months and felt the best I've felt since I was a kid. Then I had a dessert then the next night another until I couldn't balance my blood sugar anymore. Immediately, my insomnia returned then all of my symptoms returned.
Take my word for it, I was diagnosed with cfs in 1987 and fms in 1994. The adrenal glands are taxed and stressed. Fix your diet, balance blood sugar and see a huge improvement.
To me its like diabetes of the Adrenal Gland. I have to eat as if I am diabetic.
Your cfs/me/fms/pots can be reversed.
Sure but where's the link to the paper?
This woman keeps mentioning a blood test, but doesn't actually reveal what that test is. Is she merely hinting that there is a blood test in progress? This video was made 9 years ago, so there has to be a test at this point. Does anybody actually know?
Omg I just burst out in tears bc this is so me! I struggle with back pain from schuermanns disease and mild chronic scoliosis but I've got my back pain back to a manageable level but my stomach and internally I'm shaking, jittery, and feel like I want to puke every single day! I have the muscle pain and tenderness and I feel like I'm plugged into an electrically outlet bc my mind is always racing and I have a millions things I want to do but I don't feel like doing them. I never want to go out around people bc I always feel so bad so I have no friends and I'm basically home all the time. I try to work as much as possible but it's so hard to hold anything bc I'm waking up throwing up some night's and just break out in sweats after I throw up. It's miserable bc I have acid reflux on top of it and widespread pain which I think is a bad form of arthritis bc my grandma had it as well and died from bone cancer. My pepaw died at 52 from liver cancer, uncle died at 52, and my dad died at 58 with throat cancer which Dr thought was from acid reflux and Zantac but he was dead bf we could do anything and the Dr retired and we didn't see the Email in time so both our records were destroyed!
What blood tests?! Mind giving us the names?
I didn't see a date on this but seems older. I do see comments on here at least from 3 years ago.
What is the test called?
Good luck getting a diagnosis
I take 30mg. of Adderall XR daily and still have no energy. If I quadruple my medication, I have enough energy. The problem with that is I'm only prescribed 30 pills for 30 days.
Which blood tests